Pengaruh Pemberian Air Jeruk Nipis (Citrus aurantifolia) Terhadap Konsentrasi dan Motilitas Spermatozoa Mencit (Mus musculus) Setelah Terpapar Asap Rokok
https://doi.org/10.33476/jky.v27i1.779
Keywords:
Citrus aurantifolia, Mus musculus, rokok, spermatozoaAbstract
Merokok telah dikenal sebagai salah satu penyebab masalah kesehatan paru-paru, jantung, gastrointestinal, dan kesuburan. Efek asap rokok terhadap kesuburan dapat dilihat dari penurunan kualitas dan kuantitas spermatozoa. Konsumsi makanan yang mengandung vitamin C diketahui dapat menekan penurunan kuantitas dan kualitas spermatozoa perokok aktif. Tujuan penelitian ini adalah untuk mengetahui pengaruh pemberian jeruk nipis terhadap konsentrasi spermatozoa dan persentase motilitas spermatozoa abnormal Mus musculus. Pada penelitian ini dilakukan pemberian jeruk nipis sebagai sumber vitamin C pada mencit (Mus musculus) untuk menentukan pengaruh pemberian jeruk nipis terhadap konsentrasi dan motilitas spermatozoa mencit (Mus musculus) yang telah terpapar asap rokok. Hasil penelitian menunjukkan bahwa pemberian jeruk nipis sebanyak 1 mL/ 100 gram BB mencit dapat meningkatkan konsentrasi spermatozoa dan menurunkan persentase motilitas spermatozoa abnormal mencit setelah paparan asap rokok selama 10 menit.References
Alvarez JG et al., 1978. ‘Spontaneous peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa’, Journal of Andrology, 8, pp. 338–348.
Berkowitz L et al., 2018. ‘Impact of cigarette smoking on the gastrointestinal tract inflammation: Opposing effects in Crohn’s disease and ulcerative colitis’, Frontiers in Immunology, 9(JAN), pp. 1–10.
Donkersley P et al., 2018. ‘Biological, environmental and socioeconomic threats to citrus lime production’, Journal of Plant Diseases and Protection. Springer Berlin Heidelberg, 125(4), pp. 339–356.
Enejoh OS, Ogunyemi IO and Bala MS 2015. ‘Ethnomedical Importance of Citrus Aurantifolia ( Christm ) Swingle’, The Pharma Innovation Journal, 4(8), pp. 1–6.
Kementrian kesehatan RI 2015. Perilaku Merokok Masyarakat Indonesia Berdasarkan Riskesdas 2007 dan 2013, Infodatin.
Kementrian kesehatan RI 2018. Hasil utama riskesdas 2018. doi: 1 Desember 2013.
Kovac JR, Khanna A and Lipshultz LI 2015. ‘The effects of cigarette smoking on male fertility’, Postgraduate Medicine, 127(3), pp. 338–341.
Mohod K et al., 2014. ‘Circulating Lipid Peroxide and Antioxidant Status in Cigarette Smokers : An International Journal of Health Sciences and Research’, International Journal of Health Sciences and Research, 4(5), pp. 59–65.
Moretti E et al., 2012. ‘Effect of quercetin , rutin , naringenin and epicatechin on lipid peroxidation induced in human sperm’, Reproductive Toxicology, 34, pp. 651–657.
Nakada K et al., 2006. ‘Mitochondria-related male infertility’, Proceedings of the National Academy of Sciences, 103(41), pp. 15148–15153.
Nsonwu-Anyanwu A, Offor S and John I 2018. ‘Cigarette Smoke and Oxidative Stress Indices in Male Active Smokers’, Reactive Oxygen Species, 5(15), pp. 1–10.
Oyeyipo IP et al., 2011. ‘Effects of nicotine on sperm characteristics and fertility profile in adult male rats: A possible role of cessation’, Journal of Reproduction and Infertility, 12(3), pp. 201–207.
Papathanasiou G et al., 2014. ‘Effects of Smoking on Cardiovascular Function: The Role of Nicotine and Carbon Monoxide Institution of Athens (TEI-A), Greece 2. Physical Therapy Department, Technological Educational Institution of Athens (TEI-A), Greece 3. Physical Therapy Department, T’, Health Science Journal, 8(2), pp. 274–290.
Ramlau-Hansen CH et al., 2007. ‘Is smoking a risk factor for decreased semen quality? A cross-sectional analysis’, Human Reproduction, 22(1), pp. 188–196.
Shabanian S et al., 2017. ‘The effects of vitamin C on sperm quality parameters in laboratory rats following long-term exposure to cyclophosphamide’, Journal of Advanced Pharmaceutical Technology and Research, 8(9), pp. 73–79.
Sutanto EB et al., 2017. ‘THE EFFECT OF VITAMIN C AND E COMBINATION ON SPERM QUALITY AND CEMENT 8-OHdG LEVEL OF SMOKE EXPOSED RATS’, World Nutrition Journal, 1(1), pp. 28–33.
Suthutvoravut S and Kamyarat O 2016. ‘Spermicidal effects of lemon juice and juices from other natural products’, Agriculture and Natural Resources. Elsevier Ltd, 50(2), pp. 133–138.
Tommola M. et al., 2016. ‘The effect of smoking on lung function: A clinical study of adult-onset asthma’, European Respiratory Journal, 48(5), pp. 1298–1306.
Vijayprasad S, Ghongane BB and Nayak BB 2014. ‘Effect of vitamin C on male fertility in rats subjected to forced swimming stress’, Journal of Clinical and Diagnostic Research, 8(7), pp. 6–9.