Hubungan Kadar Lipid Darah Dengan Degenerative Disc Disease Berdasarkan Klasifikasi Pfirrmann Menggunakan Magnetic Resonance Imaging Lumbosacral pada Pasien Nyeri Punggung Bawah
Authors
-
Ryan Indra
-
Muhammad Ilyas
-
Mirna Muis
-
Bachtiar Murtala
-
Andi Alfian
-
Cahyono Kaelan
Keywords:
Degenerative disc diseae, Klasifikasi Pfirrmann, Serum Lipid, Status GiziAbstract
Penelitian ini bertujuan mengetahui hubungan serum lipid darah dengan degenerative disc disease berdasarkan klasifikasi pfirrmann menggunakan magnetic resonance imaging lumbosacral pada pasien nyeri punggung bawah. Penelitian ini dilaksanakan di Departemen Radiologi RS. Dr. Wahidin Sudirohusodo Makassar mulai bulan Oktober 2018 sampai Januari 2019. Subjek sebanyak 52 orang dengan rentang usia 30 - 60 tahun. Metode yang digunakan adalah uji Spearman. Hasil penelitian menunjukkan terdapat korelasi antara kadar low-density lipoprotein (LDL) dan trigliserida serum dengan degenerative disc disease dengan nilai p=0.02 (p<0.05). Semakin tinggi kadar LDL dan trigliserida maka derajat degerative disc disease cendereng semakin berat. Tidak terdapat korelasi antara HDL dengan degenerative disc disease. Secara statistik tidak terdapat korelasi antara kolesterol total dengan degenerative disc disease. Namun, didapatkan pada grafik nilai kolesterol total pada setiap derajat degenerative disc disease meningkat.
References
Chan D., Samartzis D., Karppinen J., Luk K.D.K & Cheung K.M.C 2012. The Association of Lumbar Intervertebral Disc Degeneration on Magnetic Resonance Imaging with Body Mass Index in Overweight and Obese Adults. Arthritis & Rheumatism; 64(5): 1488-96.
Hong C. H., et al. 2011. Measurement of The Normal Lumbar Intervertebralis Disc Space Using Masnetic Resonance Imaging. Asian Spine J; Juni: 4(1): 1 -6.
Jackson A. R., Dhawale A. A., Brown M. D., 2015. Association Between Intervertebral Disc Degeneration and Cigarette Smoking: Clinical and Experimental Findings. The Journal of Bone and Joint Surgery. Miami University, Miami; 1-9.
Kauppila L. I., 2009. Atherosclerosis and Disc Degeneration Low Back Pain – A Systematic Review. Elsevier; 37; 661-670.
Lawes C. M. M., Hoorn S. V., 2010. High Cholesterol; World Health Organization; Chapter 7; 391-449.
Longo U.G, Denaro L., Spiezia F., 2011. Symtomatic Disc Herniation and Serum Lipid Levels. Springer-Verlag. Rome; 20; 1658-1662.
Nagy S. A., Juhasz I., Komaromy H., 2012. Classification of Intervertebral Disc Degeneration Using Quantitative T2 Relaxion Time Measurements; European Society of Radiology; 1-18
Pannu G., Jokoi A. M., 2017. The Clinical Correlations Between Diabetes, Cigarette Smoking, and Obesity on Intervertebral Degenerative Disc Disease of The Lumbar Spine. Asian Spine Journal; 11 (3); 337-347.
Ract I., Meadeb J., 2015. A Review of The Value of MRI Signs in Low Back Pain. Diagnostic and Interventional Imaging. Elsevier; 96; 239-249.
Samartzis D., Karppinen J., Cheung J. P. Y., 2012. Disc Degeneration and Low Back Pain: Are They Fat Related Conditions ?. Global Spine Journal; 3; 133-144
Sheng B., Feng C., Zhang D., 2017. Association Between Obesity and Spinal Disease: Medical Expenditure Panel Study Analysis. International Journal of Enviromental Research and Public Health; 14; 183.
Sudoyo A.W., Setiyohadi B.,Alwi I. 2014. Buku Ajar Ilmu Penyakit Dalam. Jilid III. Edisi IV. Departemen Ilmu Penyakit Dalam Universitas Indonesia. Jakarta.
Tian W. & Qi H. 2010. Association Between Intervertebral Disc Degeneration and Disturbances of Blood Supply to The Vertebrae. Beijing Jushiutan Hospital ; 1 -10.
Urrutia J., Besa P., Campos. 2016 The Pfirrmann Classification of Lumbar Intervertebral Disc Degeneration: An Independent Inter- and Intra-Observer Agreement Assessment; Springer-Verlag. Berlin.
Zhang Y, Wang M, Si M, Li J 2016. Serum Lipid Levels Are Positively Correlated with Lumbar Disc Herniation. Lipids in Health Disease. 15-80.
