Nipah Virus Disease: A Literature Review of The Current State of the Knowledge and Management

Authors

  • Daffa Arkananta Putra Yanni YARSI University

https://doi.org/10.33476/jky.v31i2.3957

Keywords:

Nipah Virus. Zoonotic Disease, Literature Review

Abstract

Nipah viral disease is a zoonotic infection and an emerging disease caused by the Nipah virus (NiV), an RNA virus of the genus Henipavirus, family Paramyxoviridae, which is transmitted by specific types of fruit bats, mainly Pteropus spp. The NiV is highly pathogenic to a broad range of mammals and is considered to have pandemic potential due to its human-to-human transmission through close contact with infected persons. The virus is responsible for causing severe respiratory illness and deadly encephalitis in humans with the most common symptoms being altered mental status, areflexia, hypotonia, segmental myoclonus, gaze palsy, and limb weakness. There are no vaccines against NiV infection in humans and are available as the difficulty of dealing with a highly contagious and virulent virus is one of the concerns together with the opportunity of collecting human samples during the outbreaks which occur in the countries where the NiV virus spreads. Proper isolation, quarantine, and disinfection protocol including infrastructure facilities and trained personnel with protective clothing should be in place to respond quickly upon identification of any new case.

References

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Published

2025-09-26

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Section

Research Articles