Skrining Berbasis Ponsel Pintar: Alat Deteksi Midkine, Adiponectin¸ Apolipoprotein C-1, Kidney Injury Molecule-1 sebagai Biomarker Obstruksi Arteri Koroner
Authors
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Ignatius Ivan
Atma Jaya University
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Maureen Miracle Stella
Atma Jaya Catholic University of Indonesia
http://orcid.org/0000-0003-2932-3498
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Kevin Tandarto
Atma Jaya Catholic University of Indonesia
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Mariani Santosa
Atma Jaya Catholic University of Indonesia
Keywords:
Penyakit Jantung Koroner, Obstruksi Arteri Koroner, Ponsel Pintar, BiomarkerAbstract
Penyakit Jantung Koroner (PJK) adalah penyakit akibat penumpukan plak di dalam arteri koroner yang menyuplai oksigen ke jantung. Diketahui bahwa penyakit kardiovaskuler menyebabkan kematian sebanyak >17 juta orang setiap tahunnya dimana 42,3% diakibatkan oleh PJK. Melalui perkembangan teknologi kedokteran dan mengingat masyarakat dunia yang banyak memiliki ponsel pintar (6.4 triliun pengguna pada tahun 2021, maka kedua bidang ini mulai dikombinasikan. Cara deteksi biomarker ((midkine, adiponectin, apolipoprotein C-1 [ApoC-1], dan kidney injury molecule-1 [KIM-1]) melalui imunofluorosensi dengan alat portabel berbasis ponsel pintar dapat menjadi terobosan untuk mendeteksi Obstruksi Arteri Koroner yang Signifikan (OAKS). Dengan menggunakan konsep alat diagnosis portabel dan memiliki kemampuan multiplexing diharapkan 4 biomarker OAKS dapat terdeteksi dengan lebih mudah, cepat, tepat dan tanpa membutuhkan keahlian khusus sehingga pada akhirnya alat ini mampu menjangkau seluruh tingkat layanan kesehatan masyarakat terutama yang bersifat layanan primer.
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