Eosinofil dan asma

Authors

  • Elyusrar A. Jalal

https://doi.org/10.33476/jky.v13i1.1059

Keywords:

Eosinophil, granular cationic protein, remodeling

Abstract

Eosinophils are often found as dominant inflammatory cells present in the airways of asthma patients, but the importance of these white blood cells has been poorly understood. The eosinophil functional activity, like immune response in general may be beneficial or harmful for the organism. They could have an important role in the disordered repair that leads to permanently impaired function of airways tissue in asthmatic. This paper is a review focused on the relationship of eosinophil and their products with asthma.

References

Adolphson CR, Gleich GJ 1995.Eosinophils, in Holgate ST, Church MK, eds. Allergy, London: Mosby-Wolfe; 6.1-6.12.

Bochner BS 1997. Cellular adhesion and its antagonism. J Allergy Clin Immunol 100:581-585.

Denburg JA 1998. The origin of basophils and eosinophils in allergic inflammation. J Allergy Clin Immunol 102: S74-S76.

Dvorak A, Weller P, Monahan-Earley R, Letorneau L, Ackerman S 1990. Ultrastructural localization of Charcot-Leyden crystal protein (lysophospholipase) and peroxidase in macrophages, eosinophils, and extracellular matrix of the skin in the hypereosino-philic syndrome. Lab Invest 62: 590-607.

Fryer AD, Costello RW, Jacoby DB 2000. Muscarinic receptor dysfunction in asthma. Allergy Clin Immunol Internat 12: 63-67.

Gleich GJ 1991. The eosinophil in bronchial asthma. J Allergy Clin Immunol 88: 305-306.

Horn BR, Robin ED, Theodore J, Van Kessel A 1975. Total eosinophili counts in the management of bronchial asthma. N Eng J Med 292(22): 1152-1155.

Karp MW and Karp CL 2004. BIOMEDICINE: Eosinophils in asthma: Remodeling a tangled tale. Science 305: 1726-1729.

Lee JJ, Dimina D, Macias MP, Ochkur SI, McGarry MP, O’Neill KR, Protheroe C, Pero R, Nguyen T, Cormier SA, Lenkiewicz E, Colbert D, Rinaldi L, Ackerman SJ, Irvin CG, Lee NA 2004. Defining a link with asthma in mice congenitally deficient in eosinophils. Science 305: 1773-1776.

Milgrom H 2004. Anti-IgE therapy in allergic disease. Curr Opin Pediatr. 16(6): 624-627.

Rothenberg ME 1998. Eosinophilia. N Eng J Med. 338: 1592-1600.

Rothenberg ME 1999. Eotaxin. An essential mediator of eosinophil trafficking into mucosal tissue. Am J Respir Cell Mol Biol 21: 291-295.

Soth M 2004. The eosinophil in airway remodeling and hyperresponsiveness in asthma: participant or bystander?. Thorax 59: 1051.

Takenaka T, Okuda M, Kawabori S, Kubo K 1997. Extracellular release of peroxidase from eosinophils by interaction with immune complex. Clin & Exp Immunol 28:56-60.

Venge P 1993. The eosinophil granulocyte in allergic inflammation. Pediatr Allergy Immunol 104: S19-S24.

Wardlaw AJ, Brightling C, Green R, Woltmann G and Pavord I 2000. Eosinophils in asthma and other allergic diseases. British Medical Bulletin 56: 985-1003.

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Published

2019-11-20