THE The Use of Injectable Platelet-Rich Fibrin As an Alternative Treatment for Interdental Papilla Reconstruction in Black Triangle Case
Authors
-
Nastiti Mayangjati
Universitas Gadjah Mada
-
Fawzan Nur Ramadhan
Universitas Gadjah Mada
-
Vincensia Maria Karina
Universitas Gadjah Mada
Keywords:
Black triangle, Injectable PRF, papilla reconstructionAbstract
Introduction: Interdental papilla is triangular soft tissues that fill the gaps between teeth and
function as protective periodontal tissues and are important in terms of aesthetics, if
inadequate, they will form black triangles, which are blackish areas between teeth. Non-
surgical treatment of black triangle is preferred by patients as it is painless. Injectable Platelet-
Rich Fibrin (i-PRF) is a platelet concentrate derived from the patient's blood that does not
cause immunological reactions and contains growth factors for remodeling the interdental
papilla. Case Report: A 20-year-old female patient, systemically healthy, came to Prof.
Soedomo UGM Dental Hospital with complaints that the gums of the middle part of her upper
teeth had a blackish area and disturbed her confidence. An objective examination was carried
out including, gingival biotype, black triangle area, and radiographs, so it was concluded that
the black triangle was classified as class I Nordland and Tarnow and interdental papilla
reconstruction to correct the black triangle could be planned. The patient refused surgery so i-
PRF can be used as an alternative non-surgical treatment. The black triangle closed completely
after the i-PRF injection was given. Discussion: I-PRF has the ability to accelerate cell
proliferation and migration as well as angiogenesis so that it can modulate fibroblast
regeneration in the interdental papilla area. Conclusion: The use of i-PRF can be an alternative
non-surgical option for the treatment of interdental papilla reconstruction.
References
Puri K, Khatri M, Bansal M, Kumar A, Rehan M, Gupta A. A novel injectable platelet-rich
fibrin reinforced papilla reconstruction technique. Journal of Indian Society of
Periodontology. 2022 Jul;26(4):412.
Fakher I, Hazzaa HH, Abdelgawad N. Use of Injectable Hyaluronic Acid Gel and
Injectable Platelet-rich Fibrin in the Treatment of Gingival Black Triangles: A
Randomized Clinical Trial. Al-Azhar Dental Journal for Girls. 2023 Apr 1;10(2):471-7.
Singh D, Jhingran R, Bains VK, Madan R, Srivastava R. Efficacy of platelet-rich fibrin in
interdental papilla reconstruction as compared to connective tissue using microsurgical
approach. Contemporary Clinical Dentistry. 2019 Oct;10(4):643.
Mahmood ZN. Clinical Application of Hyaluronic Acid and Platelet-Rich-Fibrin in
Reconstructing Interproximal Papillae in Teeth and Implants. A Literature Review.
Bissar MW, Nasser N, El-Mofty MS. Volumetric Soft Tissue Changes After Using
Injectable Platelet-Rich Fibrin (I-PRF) Versus Subepithelial Connective Tissue Graft in
Interdental Papillae Defects: A Randomized Controlled Clinical Study. Perio J. 2022 Jul
;6(1):26-35.
Chu SJ, Tarnow DP, Tan JH, Stappert CF. Papilla proportions in the maxillary anterior
dentition. Int J Periodontics Restorative Dent 2009;29:38593.
Hassan H, Quinlan DJ, Ghanem A. Injectable plateletrich fibrin for facial rejuvenation: A
prospective, single-center study. J Cosmet Dermatol 2020;19:3213-21.
Singh G, Chauhan S, Sinha A. Regeneration Of Interproximal Attachment: Challenge In
Periodontal Therapy: A Review. Guident. 2022 Apr 1;15.
Akolu P, Lele P, Dodwad V, Khot T, Kundoo A, Bhosale N. Comparative Evaluation Of
The Effect Of Injectable Platelet Rich Fibrin (I-Prf) On Gingival Thickness In Individuals
With Thin Periodontal Phenotype–A Clinical Study.
Tarnow DP, Magner AW, Fletcher P. The effect of the distance from the contact point to
the crest of bone on the presence or absence of the interproximal dental papilla. J
Periodontol 1992;63:9956.
Shenoy B S, Punj A, Ramesh A, Talwar A. Salvaging the lost pink triangle: a case series
of papilla reconstruction. Case Reports in Dentistry. 2020 Jan 14;2020.
Shruthi S, Gujjari SK, Mallya KP. Comparison of two surgical techniques for the
reconstruction of interdental papilla. Journal of Interdisciplinary Dentistry. 2015 Jan
;5(1):17.
Faour NH, Dayoub S, Hajeer MY, Faour N, Hajeer MY. Evaluation of the Hyaluronic
Acid Versus the Injectable Platelet-Rich Fibrin in the Management of the Thin Gingival
Phenotype: A Split-Mouth Randomized Controlled Clinical Trial. Cureus. 2022 May
;14(5).
Miron RJ, Fujioka-Kobayashi M, Bishara M, Zhang Y, Hernandez M, Choukroun J.
Platelet-rich fibrin and soft tissue wound healing: a systematic review. Tissue Engineering
Part B: Reviews. 2017 Feb 1;23(1):83-99.
Chen Z, Miao D, Zhang L, Zhong L, Liu N, Chen Y. Efficacy of concentrated growth
factor with low-level laser for the regeneration of interdental papilla defects. Odontology.
Oct;110(4):795-804.
Miron RJ, Chai J, Zheng S, Feng M, Sculean A, Zhang Y. A novel method for evaluating
and quantifying cell types in platelet rich fibrin and an introduction to horizontal
centrifugation. J Biomed Mater Res A 2019;107:2257-71.
Choukroun J, Diss A, Simonpieri A, Girard MO, Schoeffler C, Dohan SL, et al.
Plateletrich fibrin (PRF): A secondgeneration platelet concentrate. Part IV: Clinical effects
on tissue healing. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:e5660.
Choukroun J, Ghanaati S. Reduction of relative centrifugation force within injectable
plateletrichfibrin (PRF) concentrates advances patients’ own inflammatory cells, platelets
and growth factors: The first introduction to the low speed centrifugation concept. Eur J
Trauma Emerg Surg 2018;44:87-95.
Fujioka-Kobayashi M, Miron RJ, Hernandez M, Kandalam U, Zhang Y, Choukroun J.
Optimized platelet rich fibrin with the low speed concept: growth factor release,
biocompatibility and cellular response. J Periodontol. 2017; 2:1-17.
Ghanaati, S., Al-Maawi, S., Herrera-Vizcaino, C., Alves, G. G., Calasans-Maia, M. D.,
Sader, R., Kirkpatrick, C. J., Choukroun, J., Bonig, H., & Mourão, C. (2018). A Proof of
the Low Speed Centrifugation Concept in Rodents: New Perspectives for In Vivo
Research. Tissue engineering. Part C, Methods, 24(11), 659–670. https://doi.org/10.
/ten.TEC.2018.0236.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Nastiti Mayangjati
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
This work is licensed under a CC Attribution-ShareAlike 4.0
