Gambaran Klinis Stomatitis Aftosa Rekuren pada Pasien dengan Infeksi Human Immunodeficiency Virus (Laporan Kasus)

Nurfianti Nurfianti, Siti Aliyah Pradono

Abstract


Recurrent oral ulceration usually induced pain and influence patient’s quality of life. Reccurent Aphthous Stomatitis (RAS) is a common disorder with recurring ulcers, affecting the oral mucosa, painful and no other signs of systemic disease. Human Immunodeficiency Virus (HIV) is considered as a predisposing factor for RAS. Lesion of RAS associated with HIV, usually more severe, longer lasting to healing and non specific clinical features. This case report describe clinical features of recurrent oral ulceration in HIV patient.  A 23 year old female came with complaint oral ulceration in soft palate and tongue since 2 months ago. Patient was diagnosis HIV since seven years ago. Several examinations were done to explore possibility of opportunist infection in HIV patient. Intra oral examination showed regular ulcer, with yellowish base, surrounding erythematous halo. The locations of ulcer were in labial mucosa, dorsum and ventral of the tongue, and soft palate. Ulceration in keratinized mucosa and non keratinized mucosa, gives un-specific features mimicking Tuberculous oral ulcer but in this case there was no indurations on all ulcer. Based on anamnesis and clinical examination, the diagnosis of this case is RAS with differential diagnosis of Tuberculous oral ulcer. The therapy given was gold standard of RAS, the outcome was successful without TB therapy. RAS on HIV Patient can give unspecific clinical features, mimicking oral manifestation of opportunist infection commonly occurred in HIV patient.

Keywords


reccurent aphthous stomatitis, HIV, clinical features, tuberculous oral ulcer

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References


Akkoca, A.N., Özdemir, Z.T., Yan?k, S., Ar?ca, S.G., Yalçin, H., Özler, G.S. 2014. The frequency and etiology of recurrent apthous stomatitis in helicobacter pylori posit?ve patients. Am J Intern Med.;2(4):72–8.

Babaee, N., Zabihi, E., Mohseni. S., Moghadamnia, A. 2012. Evaluation of the therapeutic effects of Aloe vera gel on minor recurrent aphthous stomatitis. Dent Res J.;9(4):381–5.

Belenguer-Guallar, I., Jiménez-Soriano, Y., Claramunt-Lozano, A. 2014. Treatment of recurrent aphthous stomatitis. A literature review. J Clin Exp Dent. 6(2):e168–74.

Brocklehurs,t P., Tickle, M., Glenny, A.,M., Lewis, M., Pemberton, M.N., Taylor, J., 2012. Systemic interventions for recurrent aphthous stomatitis (mouth ulcers). Cochrane database Syst Rev. 9(9):1–7.

Caputo, B.V., Noro, Filho, G.A., Dos Santos, C.C., Okida, Y., Giovani, E.M. 2012. Laser Therapy of Recurrent Aphthous Ulcer in Patient with HIV Infection. Case Rep Med.:1–3.

Chapple, I.L., Hamburger, J. 2000. The significance of oral health in HIV disease. Sex Transm Infect. 76(4):236–43.

Cimaz, I.R. 2002. Safety and Efficacy of Aloclair TM Gel in the treatment of Oral Aphthous Lesions in Children : Preliminary Findings from an Open Pilot Study. Aloclair Gel Trial.;(March):1–6.

Coogan, M.M., Greenspan, J., Challacombe, S.J. 2005. Oral lesions in infection with human immunodeficiency virus. World Heal Organ Bull World Heal Organ. 83(9):700–6.

Davoodi, P., Hamian, M., Nourbaksh, R., Ahmadi Motamayel, F. 2010. Oral Manifestations Related To CD4 Lymphocyte Count in HIV-Positive Patients. J Dent Res Dent Clin Dent Prospects. 4(4):115–9.

Dixit, R., Sharma, S., Nuwal, P. 2008. Tuberculosis of Oral Cavity. Indian J Tuberc. 55:51–3.

Gnanasundaram, N. Key to Diagnose HIV / AIDS Clinically through its Oral Manifestations. J Indian Acad Oral Med Radiol.2010;22:119–25.

Gorsky, M.B.E.J, 2007. Topical minocycline and tetracycline rinses in treatment of recurrent aphthous stomatitis: a randomized cross-over study. Dermatology online. 13(2).

Hudson. J. 2014. Recurrent Aphthous Stomatitis : Diagnosis and Management in Primary Care Recurrent Aphthous Stomatitis : Diagnosis and Management in. J Patient-Centered Res Rev. 1(4):197–200.

Jain. P, Jain. I. 2014. Oral Manifestations of Tuberculosis : Step towards Early Diagnosis. Journa Clin Diagnostic Res. 8(12):18–21.

Kapoor, P., Sachdeva, S., Sachdeva, S. 2011. Topical Hyaluronic Acid in The Management of Oral Ulcers. Indian J Dermatol. 56(3):300–2.

Miziara, I.D., Araujo Filho, B.C,, Weber, R. 2005. AIDS and Recurrent Aphthous Stomatitis. Braz J Otorhinolaryngol.71(4):517–20.

Phail, M. S.J G. 1997. Oral ulceration in HIV infection: investigation and pathogenesis. UCSF Dept Stomatol. 3(1):190–3.

Preeti, L., Magesh, K., Rajkumar, K., Karthik, R. 2011. Recurrent aphthous stomatitis. J Oral Maxillofac Pathol. 15(3):252–6.

Scully, C., Gorsky, M., Lozada-Nur, F. 2003. The diagnosis and management of recurrent aphthous stomatitis: a consensus approach. J Am Dent Assoc. 134(2):200–7.

Vijayabala, G.S., Kalappanavar, A., Annigeri, R., Sudarshan, R., Shettar, S. 2013. Single application of topical doxycycline hyclate in the management of recurrent aphthous stomatitis. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;16(4):440–6.

Woo, S.B., Greenberg, M.S. 2015. Burket’s Oral Medicine. 12th ed. Glick M, editor. Connecticut: People’s Medical Publishing House—USA.173-182.




DOI: https://doi.org/10.33476/ms.v6i2.1202

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