Obstructive Sleep Apnea dan Gagal Jantung
Authors
-
Sidhi Laksono Purwowiyoto
RSUD Pasar Rebo, East Jakarta
FK Universitas YARSI
Keywords:
obstructive sleep apnea, heart failure, pathophysiologyAbstract
Obstructive sleep apnea (OSA) is a part of sleep-disordered breathing which is commonly found in the population of heart failure. Epidemiological studies have shown significant independent associations between OSA and heart failure. OSA plays an important role in the pathogenesis and progression of heart failure. Several pathogenesis are the mechanical effect, activation of sympathetic, inflammation process, and endothelial dysfunction. These can impair myocardial contractility and cause development and progression of heart failure. However, the prevalence OSA is only the “tip of the iceberg” due to the difficulty in diagnosis. Most of OSA patients, particularly in the heart failure population, have no complaint of the sleepiness
References
Somers VK. Chapter 79: Sleep Apnea and Cardiovascular Disease. In: Bonow RO, Mann DL, Zipes DP, Libby P, editors. Braunwald's Heart Disease A Textbook of Cardiovascular Medicine Ninth Edition. Philadelphia: Saunders Elsevier; 2012. p.1719-26.
Bradley TD, Floras JS. Sleep apnea and heart failure: Part I: obstructive sleep apnea. Circulation 2003;107(12):1671-8.
Ferreira S, Winck J, Bettencourt P, Rocha-Goncalves F. Heart failure and sleep apnoea: to sleep perchance to dream. Eur J Heart Fail 2006;8(3):227-36.
Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force. Sleep 1999;22(5):667-89.
Somers VK, White DP, Amin R, Abraham WT, Costa F, Culebras A, et al. Sleep apnea and cardiovascular disease: an American Heart Association/american College Of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council On Cardiovascular Nursing. In collaboration with the National Heart, Lung, and Blood Institute National Center on Sleep Disorders Research (National Institutes of Health). Circulation 2008;118(10):1080-111.
Lattimore JD, Celermajer DS, Wilcox I. Obstructive sleep apnea and cardiovascular disease. J Am Coll Cardiol 2003;41(9):1429-37.
McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Bohm M, Dickstein K, et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J 2012;33(14):1787-847.
Wexler L, Javaheri S. Sleep apnea is linked to heart failure, but does treatment improve outcome? Cleve Clin J Med 2005;72(10):929-36.
Arzt M, Bradley TD. Treatment of sleep apnea in heart failure. Am J Respir Crit Care Med 2006;173(12):1300-8.
Kasai T, Bradley TD. Obstructive sleep apnea and heart failure: pathophysiologic and therapeutic implications. J Am Coll Cardiol 2011;57(2):119-27.
Wilcox I, McNamara SG, Wessendorf T, Willson GN, Piper AJ, Sullivan CE. Prognosis and sleep disordered breathing in heart failure. Thorax 1998;53 Suppl 3:S33-6.
Shahar E, Whitney CW, Redline S, Lee ET, Newman AB, Javier Nieto F, et al. Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study. Am J Respir Crit Care Med 2001;163(1):19-25.
Young T, Peppard PE, Gottlieb DJ. Epidemiology of obstructive sleep apnea: a population health perspective. Am J Respir Crit Care Med 2002;165(9):1217-39.
Gottlieb DJ, Yenokyan G, Newman AB, O'Connor GT, Punjabi NM, Quan SF, et al. Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the sleep heart health study. Circulation 2010;122(4):352-60.
Stradling JR, Davies RJ. Sleep. 1: Obstructive sleep apnoea/hypopnoea syndrome: definitions, epidemiology, and natural history. Thorax 2004;59(1):73-8.
Sin DD, Fitzgerald F, Parker JD, Newton G, Floras JS, Bradley TD. Risk factors for central and obstructive sleep apnea in 450 men and women with congestive heart failure. Am J Respir Crit Care Med 1999;160(4):1101-6.
Onat A, Hergenc G, Yuksel H, Can G, Ayhan E, Kaya Z, et al. Neck circumference as a measure of central obesity: associations with metabolic syndrome and obstructive sleep apnea syndrome beyond waist circumference. Clin Nutr 2009;28(1):46-51.
Peppard PE, Young T, Palta M, Skatrud J. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med 2000;342(19):1378-84.
Arzt M, Young T, Finn L, Skatrud JB, Ryan CM, Newton GE, et al. Sleepiness and sleep in patients with both systolic heart failure and obstructive sleep apnea. Arch Intern Med 2006;166(16):1716-22.
Buxbaum SG, Elston RC, Tishler PV, Redline S. Genetics of the apnea hypopnea index in Caucasians and African Americans: I. Segregation analysis. Genet Epidemiol 2002;22(3):243-53.
Ryan CM, Bradley TD. Pathogenesis of obstructive sleep apnea. J Appl Physiol 2005;99(6):2440-50.
Dempsey JA, Veasey SC, Morgan BJ, O'Donnell CP. Pathophysiology of sleep apnea. Physiol Rev 2010;90(1):47-112.
