Pengaruh Bising Pesawat Udara terhadap Jumlah Sel NK (CD56 + CD16 + CD3 ) pada Masyarakat di Sekitar Bandara Adi Sumarmo Boyolali
Authors
-
Hartono Hartono
Department of Physiology, Sebelas Maret University School of Medicine, Solo
Keywords:
Aircraft noise, Natural Killer Cell, Adi Sumarmo AirportAbstract
Exposure to noise constitutes a health risk. There is sufficient scientific evidence that noise exposure can induce hearing impairment, hypertension and ischemic heart disease, annoyance, sleep disturbance, and decreased school performance. For other effects such as changes in the immune system and birth defects, the evidence is limited.The aims of this study was to find out the effect of the aircraft noise level to the number of Natural Killer Cell (CD56+CD16+CD3) among people in the area of Adi Sumarmo Airport Boyolali.The research finding was expected to contribute to the science development and to give benefits for local government and among people in the Area of Adi Sumarmo Airport in preventing the effect of noise. The research design was an analytical survey with a cross sectional approach, taking location at the Dibal and Gagak Sipat Village, Ngemplak Sub district, Boyolali District. The work was conducted from Juny to October 2008. The number of subjects involved were 57. They were divided into 3 groups; Group 1 was exposed 52.17 dB of noise level (19 respondents); Group 2 was exposed 71.79 dB of noise level (19 respondents); and Group 3 was exposed 92.29 dB of noise level (19 respondents). The samples were taken usingsimple random sampling. The data were analyzed by Anova followed by Post Hoc Test using LSD test completed with Homogenous Subsets. Based on the results of the analysis, a conclusion was drawn that there was a significant effect of the aircraft noise level to the number of Natural Killer Cell (CD56+CD16+CD3) among people in the area of AdiSumarmo Airport Boyolali.References
Arifiani N 2004. Pengaruh kebisingan terhadap kesehatan tenaga kerja.Cermin Dunia Kedokteran. No.144 : 24-28
Cheng Zheng K, Ariizumi M 2007. Modulation of immune functions and oxidative status induced by noise stress.J Occup Health ;49 ; 32-38.
Cohen S, Kessler RC, Gordon LU 1995. Measuring Stress, New York: Oxford University Press, pp :181-182.
Cooper MA, Fehniger TA, Caligiuri MA 2001. The biology of human natural killer-cell subsets. Trends Immunol; 22(11):633-40.
Dhanalakshmi S, Srikumar R, Manikandan S, Parthasarathy NJ, Devi RS 2006. Antioxidant property of Triphala on cold stress induced oxidative stress in experimental Rats. J Health Science;52(6) ; 843-847.
Dobbin JP, Harth M, McCain GA et al. 1991. Cytokine production and lymphocyte transformation during stress.Brain Behav Immun; 5: 339–348.
Ganong WF 2003. Review of Medical Physiology. 22 Ed. New York: Lange Medical Books/McGrwHill: 515-531.
Guyton AC, John E, Hall 2006. Textbook of Medical Physiology.11
ed. Elsevier Inc.Philadelphia, Pennsylvania. P : 429-438.
Gobeirno DeAragon 1998. Win Episcope 2.0 Programe. University of Edinburgh.
Haines MM, Stansfeld SA, Job Soames RF, Berglund B, Head J 2001. A Follow-up study of effects of chronic aircraft noise exposure on child stress responses and cognition. International Journal of Epidemiology;30 page ; 839-845.
Hartono 2005. Pengaruh perbedaan intensitas kebisingan terhadap sindroma dispepsia pada tenaga kerja di PT. Kusuma Hadi Santosa Karanganyar.Biosmart. Vol 7 (2) : 131-134.
Hartono 2006. Perbedaan intensitas kebisingan pengaruhnya terhadap jumlah limfosit pada tikus putih (Rattus novergicus). Enviro. Vol 7,No.1.
Hartono 2006. Pengaruh perbedaan intensitas kebising-an terhadap jumlah limfosit pada masyarakat di sekitar bandara Adi Sumarmo Boyolali.Enviro.Vol 7, No.2.20-24.
Hartono Muthmainah, 2007, Pengaruh perbedaan intensetas kebisingan terhadap gambaran struktur histologi lambung pada tikus putih (Rattus norvegicus), Jurnal Kedokteran Yarsi 15 (2) : 133-138.
Hartono, Isna Q, Margono 2007. Pengaruh paparan bisingpesawat udara terhadap struktur histologi duodenum pada tikus putih (Rattus norvegicus), EnviroVol 8, No.1. 33-36.
Karvanen M, Mikheev MI 1986. Epidemiology of Occupational Health. Europe: WHO Regional Publications,p: 27.
Keputusan Direktur Jenderal Perhubungan Udara No: SKEP/109/VI/2000 tanggal 6 Juni 2000 Tentang Petunjuk Pelaksanaan Pembuatan Kawasan Kebisingan Bandar Udara.
Kusmiati A, Meilawati Y, Yustiani dan Mubiarti E 2006. Valuasi ekonomi kebisingan pesawat udara di pemukiman sekitar bandara Husein Sastranegara. Jurnal Teknik Lingkungan. Edisi Khusus. 241-248
Kresno Siti Boedina 2001. Diagnosis dan Prosedur Laboratorium. Fakultas Kedokteran Universitas Indonesia. Jakarta. 30-33.
Megan AC, Todd AF and Michael AC 2001. Review of the biology of human natural killer-cell subsets. Trends in Immunology.Volume 22, Issue 11, Pages 633-640.
Megan AC, Todd AF, Sarah CT, Kenneth SC, Bobak AG, Tariq G, William ECand Michael AC 2001. Human natural killer cells: a unique innate immunoregulatory role for the CD56 bright subset.Blood, Vol. 97, No. 10, pp. 3146-3151
Melamed S, Luz J, Green MS 1992. Noise exposure, noise annoyance and their relation to psychological distress, accident and sickness absence among blue-collar workers-the Cordis Study.Lsr. J. MedSci28:629-635.
Morikawa Y, Higashiguchi KK, Tanimoto C, Hayashi M, Oketani R, Miura K, Nishijo M, Nakagawa H 2005. A Cross-sectional study on the relationship of sob Stress with Natural Killer Cell activity and Natural Killer Cell subsets among healthy nurses. Journal of Occupational Health; 47; 378-383.
Nagao F, Suzui M, Takeda K, Yagita H and Okumura K 2000. Mobilization of NK cells by exercise: downmodulation of adhesion molecules on NK cells by catecholamines. Am J Physiol Regulatory Integrative Comp Physiol279:1251-1256.
Padgett D and Glaser R 2003. How stress influences the immune response.Trends in Immunology. Vol.24 No.8 page; 444-448
Passchier-Vermeer W and Passchier Wim F 2000. Noise Exposure and Public Health. Environmental Health Perspectives.Vol 108, suplement 1; 123-131.
Poetra Bagoes R, Samiyono B, Pelitasari R 2007. Petunjuk Pengukuran dan Perhitungan Kebisingan Bandar Udara dalam WECPNL. Direktorat Jenderal Perhubungan Udara Departemen Perhubungan. Jakarta Pusat.
Putra ST 2005. ParadigmaPsikoneuroimunologi Menuju ke Disciplines-Hybrid. Graha Masyarakat Ilmiah Kedokteran (Gramik), Fakultas Kedokteran UNAIR-RSU Dr Soetomo, Surabaya : 1-15.
Ronald De Klout E 2003. Noise, brain and stress. Endocrine Regulation,Vol 37 : 51-68.
Roestam AW 2004. Program konservasi pendengaran di tempat kerja. Cermin Dunia Kedokteran. 144. page: 29-33.
Sindusakti J 2000. Dampak kebisingan pesawat terhadap kesehatan penduduk lingkungan pemukiman sekitar landasan bandara Adi Sumarmo Boyolali, (Tesis), Program Studi Ilmu Lingkungan Program Pasca Sarjana Universitas Sebelas Maret, Surakarta.
Srikumar R, Parthasarathy NJ, Manikandan S, Muthuvel A, Rajamani R, Sheeladevi R 2007. Immunomodula-tory effect of Thripala during experimentally induced noise stress in Albino rats.J Health Science; 53(1); 142-145.
Suzui M, Kawai T, Kimura H, Takeda K, Yagita A, Okumora K, Shek PN, Shepard RJ 2004. Natural killer cells lytic activity and CD 56dim and CD 56 bright cell distribution during and after intensive training.Journal Appl physiol96 : 2167-2173.
